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KMID : 0438219790160010299
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Korea University Medical Journal
1979 Volume.16 No. 1 p.299 ~ p.306
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A Study on the Effect of Hibon^(®) (Riboflavin tetrabutyrate) on Arteriosclerotic Retinopathy, Diabetic Retinopathy and Cataract
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Abstract
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Soon after the discovery of riboflavin, it was recognized that a deficiency of riboflavin was
associated with disorders of lid, ,cornea, lens and retina.
This study was devised to observe the effect of riboflavin tetrabutyrate on the metabolic changes in arteriosclerotic retinopathy, diabetic retinopathy and cataract.
The experiment was carried out on 30 adult humans with arteriosclerotic retinopathy, diabetic
ietinopathy and cataract.
After each case was treated with riboflavin tetrabutyrate, visual acuity, retinal change and
cholesterol level in serum were determined.
The result obtained from this experiment are summarzed as follows;
1. In arteriosclerotic retinopathy, visual improvement is noted in 46% of 13 cases. Serum cholesterol level is decreased. 32mg/dl on an average.
2. In diabetic retinopathy, visual improvement is noted in 43% of 14 cases. serum cholesterol level is slightly increased 0.9mg/dl on an average.
3. In. cataract, visual improvement is. not noted. serum cholesterol level is decreased 10.2mg
/dl on.ani -;average.
4. There was no side effect oft, riboflavin tetrabutyrate therapy.
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